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KMID : 1094020170340020094
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Journal of Veterinary Clinics
2017 Volume.34 No. 2 p.94 ~ p.97
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Long-term Chemotherapy with Lomustine Plus Hydroxyurea for Choroid Plexus Papilloma in a Schnauzer Dog
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Jung Dong-In
Song Joong-Hyun
Jung Hae-Won
An Su-Jin
Hwang Tae-Sung
Lee Hee-Chun
Sur Jung-Hyang
Cho Kyu-Woan
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Abstract
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A 10-year-old male Schnauzer dog presented with a 1-week history of ataxia, right-sided hemiparesis, and right-sided head tilt. On the basis of magnetic resonance imaging (MRI) with neurological examination and cerebrospinal fluid analysis results, a primary brain tumor was suspected. Therapy with imatinib mesylate plus hydroxyurea for 7 weeks was not effective and clinical signs worsened. Chemotherapy was then changed to lomustine plus hydroxyurea. Although the existing clinical signs continued, they did not deteriorate. No change in mass size was observed in subsequent MRI. The subject suddenly died from dyspnea 388 days after initial presentation. In this case, choroid plexus papilloma was definitively diagnosed based on histopathological findings.
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KEYWORD
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choroid plexus papilloma (CPP) , dog , hydroxyurea , imatinib mesylate , lomustine (CCNU)
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